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Tool to Estimate Short-Term Risk for Ischemic Stroke Recurrence
A new tool to assess 90-day risk for ischemic stroke recurrence, the RRE-90 (http://www.nmr.mgh.harvard.edu/RRE/), might help clinicians identify patients most in need of prompt follow-up.
A retrospective analysis of the tool in some 1400 patients, published in Neurology, showed that a combination of clinical and, when available, MRI features had sufficient calibration and good discrimination in predicting early recurrent stroke. The independent predictors included history of TIA or stroke, image findings, and stroke etiology. The model held up well in a small validation cohort.
Both the study authors and editorialists emphasize that the tool must be validated prospectively in a multicenter study, particularly to account for possible differences in stroke treatment among centers, before being used widely.
LINK(S):
Neurology article (Free abstract; full text requires subscription)
Neurology editorial (Subscription required)
RRE-90 site (Free)
Published in Physician's First Watch December 17, 2009
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