- Home>
- Medical News from Journal Watch>
- Medical News
Like this article?
Get free daily
medical news
from Physician's
First Watch.
Preeclampsia Marks Increased Risk for End-Stage Renal Disease Later in Life
Preeclampsia may portend end-stage renal disease (ESRD), reports the New England Journal of Medicine.
Researchers retrospectively examined outcomes among some 570,000 women who delivered singleton infants at 16 weeks' gestation or later in Norway. ESRD subsequently developed in roughly 480 women (average time to diagnosis, 17 years).
Women with preeclampsia during their first pregnancy were nearly five times as likely to develop ESRD as those without preeclampsia. Risk was even higher when the preeclamptic pregnancy resulted in a low-birth-weight or preterm infant. Adjustment for multiple confounders did not significantly alter the findings.
The researchers and editorialists discuss potential underlying mechanisms — for example, the same factors might cause both preeclampsia and renal disease. In Journal Watch Women's Health, Sandra Carson concludes: "Clinicians would be wise to note histories of preeclampsia in their patients, keeping in mind that these women might require screening for renal disease later in life."
LINK(S):
NEJM article (Free abstract; full text requires subscription)
NEJM editorial (Subscription required)
Journal Watch Women's Health summary (Subscription required)
Published in Physician's First Watch August 21, 2008
Your Remark:
To ensure that your Reader Remark is not formatted as one long paragraph, precede new paragraphs with either a blank line or an indentation.