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Diabetes and Depression — A Two-Way Street
Depression may modestly increase the risk for incident type 2 diabetes — and treated diabetes may increase the risk for depression — reports JAMA.
Researchers examined associations between diabetes and depression among roughly 6800 adults aged 45 to 84 who were without cardiovascular disease at enrollment.
The first analysis, conducted among the 5200 subjects without baseline diabetes, found that those with baseline depression had significantly increased risk for developing diabetes during 3 years' follow-up. Adjustment for lifestyle factors, however, attenuated this association.
In the second analysis, comprising 4800 adults without depression at baseline, those with treated diabetes had significantly increased risk for depression during follow-up — an association that persisted in fully adjusted analyses.
The authors call for studies to "determine whether interventions aimed at modifying behavioral factors associated with depression will complement current type 2 diabetes prevention strategies." They also suggest that providers consider routine depression screening among patients under treatment for type 2 diabetes.
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JAMA article (Free)
Published in Physician's First Watch June 18, 2008
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- Diabetes and depression
Dr Anne White, 23 Sep 2009 11:51 AM EST
I didn't see anywhere in the article a listing of antidepressant medications that patients were taking. If not accounted for... [more] - Diabetes abd Depression
Bernard A. Yablin, URMC-retired, 23 Sep 2009 11:11 AM EST
Any relationships to bipolar disorder?
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