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ACIP Withdraws Preference for ProQuad Vaccine Due to Seizures

The CDC's Advisory Committee on Immunization Practices has withdrawn its expressed preference for the ProQuad vaccine for protection against measles, mumps, rubella, and chickenpox due to a higher rate of seizures in pediatric patients, according to an Associated Press story.

In a study presented to the committee, children aged 12 to 23 months who received the vaccine had double the rate of seizures as children who got separate vaccinations for MMR and chickenpox. This equates to one additional case of convulsion per 2000 vaccinations.

Previously, the committee expressed a preference for ProQuad, since it would expose children to fewer needlesticks.

LINK(S):

Associated Press story (Free)

Published in Physician's First Watch February 28, 2008

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