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ACIP Offers Guidelines on Recently Approved Combination Vaccines for Children
The Advisory Committee on Immunization Practices has issued recommendations on using two combination vaccines for children in MMWR. The FDA approved both vaccines in June.
DTaP-IPV (Kinrix) — a combined diphtheria and tetanus toxoids and acellular pertussis and inactivated poliovirus vaccine — is indicated as the fifth dose of the DTaP series and fourth dose of the IPV series. Children aged 4 to 6 years are eligible for the new vaccine if they received DTaP (Infanrix) or DTaP-Hepatitis B-IPV (Pediarix) as the first three doses and DTaP (Infanrix) as the fourth dose.
DTaP-IPV/Hib (Pentacel) is a combined diphtheria and tetanus toxoids and acellular pertussis, inactivated poliovirus, and Haemophilus influenzae type B conjugate vaccine. It's indicated as a four-dose series at ages 2, 4, 6, and 15 to 18 months.
LINK(S):
MMWR article on Kinrix (Free)
MMWR article on Pentacel (Free)
Physician's First Watch coverage of approval of Kinrix and Pentacel (Free)
Published in Physician's First Watch October 3, 2008
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